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Evaluation of repositories for sharing individual-participant data from clinical studies

Data repositories have the potential to play an important role in the effective and safe sharing of individual-participant data (IPD) from clinical studies. We analysed the current landscape of data repositories to create a detailed description of available repositories and assess their suitability for hosting data from clinical studies, from the perspective of the clinical researcher. New publica

https://www.lupop.lu.se/article/evaluation-repositories-sharing-individual-participant-data-clinical-studies - 2025-10-05

A natural history model for planning prostate cancer testing: Calibration and validation using Swedish registry data.

Recent prostate cancer screening trials have given conflicting results and it is unclear how to reduce prostate cancer mortality while minimising overdiagnosis and overtreatment. Prostate cancer testing is a partially observable process, and planning for testing requires either extrapolation from randomised controlled trials or, more flexibly, modelling of the cancer natural history. New publicati

https://www.lupop.lu.se/article/natural-history-model-planning-prostate-cancer-testing-calibration-and-validation-using-swedish - 2025-10-05

Uppsala Longitudinal Adolescent Depression Study (ULADS).

To present the Uppsala Longitudinal Adolescent Depression Study, initiated in Uppsala, Sweden, in the early 1990s. The initial aim of this epidemiological investigation was to study the prevalence, characteristics and correlates of adolescent depression, and has subsequently expanded to include a broad range of social, economic and health-related long-term outcomes and cost-of-illness analyses. Ne

https://www.lupop.lu.se/article/uppsala-longitudinal-adolescent-depression-study-ulads - 2025-10-05

Digit@LTH breakfast seminar: Open Collaborative Data

In a prestudy project LTH, RISE and Mobile Heights have run workshops with companies and public agencies to explore bridges and barriers for Swedish companies regarding sharing data between private and public stakeholders. The area is till in its infancy, but we have identified several interesting potentials to utilise and important hinders to address. This breakfast seminar will summarise the fin

https://www.lupop.lu.se/article/digitlth-breakfast-seminar-open-collaborative-data - 2025-10-05

Effect of early supported discharge after stroke on patient reported outcome based on the Swedish Riksstroke registry.

The efficacy of early supported discharge (ESD) has not been tested in current stroke care setting, which provide relatively short hospital stays, access to hyper-acute therapies and early carotid stenosis interventions. This study aimed to compare patient-reported outcome measures (PROM) among patients with stroke that received modern stroke unit care with or without ESD. New publication in BMC N

https://www.lupop.lu.se/article/effect-early-supported-discharge-after-stroke-patient-reported-outcome-based-swedish-riksstroke - 2025-10-05

Flaunting our assets. Making the most of the Nordic registry goldmine: Cerebral palsy as an example.

To describe the early experiences of a Nordic multidisciplinary cerebral palsy (CP) registry research program combining data from national medical quality registries, follow-up programs and cohort data, in addition to data from other national registries; to explore the scientific and practical uses of such research, and provide recommendations for facilitating similar work in the future. New publi

https://www.lupop.lu.se/article/flaunting-our-assets-making-most-nordic-registry-goldmine-cerebral-palsy-example - 2025-10-05

Vägval för framtidens forskningssystem

Trots stora satsningar på forskning halkar Sverige efter i forskningskvalitet. Under detta frukostseminarium presenterar Vetenskapsrådet tolv särskilt angelägna punkter för ett svenskt forskningssystem i världsklass. Datum: 21 maj 2019Tid: 08.30-09.30Arrangör: VetenskapsrådetSvensk forskning står inför ett antal utmaningar. Vi satsar mycket pengar på forskning, har en befolkning med högt förtroend

https://www.lupop.lu.se/article/vagval-framtidens-forskningssystem - 2025-10-05

Pint of Science

Pint of Science is an annual science festival that takes place every May and brings researchers to local fun places to tell you aout the latest happenings in the world of science. The perfect opportunity for you to meet the men and women shaping the science of tomorrow. Come and share a unique moment with them! Read more here.

https://www.lupop.lu.se/article/pint-science - 2025-10-05

Key Concepts and Principles for Design and Critical Interpretation of Nordic Register-Based Studies

NOTE! Application deadline is May 15! The course will cover central concepts and principles for design and critical interpretation of Nordic register-based studies, taking ethical considerations and legal principles into consideration as well as aspects of Open Science. More information and registration  

https://www.lupop.lu.se/article/key-concepts-and-principles-design-and-critical-interpretation-nordic-register-based-studies - 2025-10-05

De-identified linkage of data across separate registers: a proposal for improved protection of personal information in registry-based clinical research.

Over the last decades the advent of digital documentation has provided research communities with valuable resources of information for clinical research. To utilize the potential of information about patients, their health care, and its outcome that is already available in different registers, the possibility to cross-reference information from different registers is inevitably required. New publi

https://www.lupop.lu.se/article/de-identified-linkage-data-across-separate-registers-proposal-improved-protection-personal-0 - 2025-10-05

Mini Review on the Use of Clinical Cancer Registers for Prostate Cancer: The National Prostate Cancer Register (NPCR) of Sweden.

The aim of this mini-review was to describe the structure and the organization of the National Prostate Cancer Register (NPCR) with some examples on how data in NPCR have affected prostate cancer care in Sweden. New publication in Frontiers in medicine.Read more here

https://www.lupop.lu.se/article/mini-review-use-clinical-cancer-registers-prostate-cancer-national-prostate-cancer-register-npcr - 2025-10-05

International variation in survival after out-of-hospital cardiac arrest: A validation study of the Utstein template.

The Utstein factors explained 51% of the variation in survival to hospital discharge among multiple large geographically separate EMS agencies. This suggests that quality improvement and public health efforts should continue to target modifiable Utstein factors to improve OHCA survival. Further study is required to identify the reasons for the variation that is incompletely understood. New publica

https://www.lupop.lu.se/article/international-variation-survival-after-out-hospital-cardiac-arrest-validation-study-utstein-template - 2025-10-05

Is the Smog Lifting?

Six main points of this article, at least at heart, are clear, documented, and convincing. In simple terms, these points are the following: (1) causal inference for certain questions in environmental epidemiology, such as studying the health effects of climate change, is difficult; (2) traditional methods have worked quite well for certain problems in environmental epidemiology; (3) additionally,

https://www.lupop.lu.se/article/smog-lifting - 2025-10-05